2024

  • [DOI] Boulch, M. L.; Jacquet, E.; Nhiri, N.; Shmulevitz, M.; Jaïs, P.. Rational Design of an Artificial Tethered Enzyme for Non-templated Post-transcriptional Mrna Polyadenylation by the Second Generation of the C3P3 System. Scientific Reports 2024, 14 (1). doi:10.1038/s41598-024-55947-0
  • [DOI] Lim, W.; Costa, M. M. D.; Godefroy, K.; Jacquet, E.; Gragert, L.; Rondof, W.; Marchais, A.; Nhiri, N.; Dalfovo, D.; Viard, M.; Labaied, N.; Khan, A.; Dessen, P.; Romanel, A.; Pasqualini, C.; Schleiermacher, G.; Carrington, M.; Zitvogel, L.; Scoazec, J.-Y.; Geoerger, B.; Salmon, J.. Divergent HLA Variations and Heterogeneous Expression but Recurrent HLA Loss-of- Heterozygosity and Common HLA-B and TAP Transcriptional Silencing Across Advanced Pediatric Solid Cancers. Frontiers in Immunology 2024, 14. doi:10.3389/fimmu.2023.1265469

2023

  • [DOI] Alvaro-Aranda, L.; Petitalot, A.; Djeghmoum, Y.; Panigada, D.; Singh, J.; Ehlén, Å.; Vugic, D.; Martin, C.; Miron, S.; Contreras-Perez, A.; Nhiri, N.; Boucherit, V.; Lafitte, P.; Dumoulin, I.; Rouleau, E.; Jacquet, E.; Feliubadaló, L.; Valle, J.; Stoppa-Lyonnet, D.; Zinn-Justin, S.; Lázaro, C.; Caputo, S.; Carreira, A.. The BRCA2 R2645G Variant Increases DNA Binding and Induces Hyper-recombination. Nucleic Acids Research 2023. doi:10.1093/nar/gkad1222
  • [DOI] Pavlidou, N.; Dobrev, S.; Beneke, K.; Reinhardt, F.; Pecha, S.; Jacquet, E.; Abu-Taha, I.; Schmidt, C.; Voigt, N.; Kamler, M.; Schnabel, R.; Baczkó, I.; Garnier, A.; Reichenspurner, H.; Nikolaev, V.; Dobrev, D.; Molina, C.. Phosphodiesterase 8 Governs Camp/pka-dependent Reduction of L-type Calcium Current in Human Atrial Fibrillation: A Novel Arrhythmogenic Mechanism. European Heart Journal 2023, 44 (27), 2483–2494. doi:10.1093/eurheartj/ehad086

2022

  • [DOI] Malard, F.; Jacquet, E.; Nhiri, N.; Sizun, C.; Chabrier, A.; Messaoudi, S.; Dejeu, J.; Betzi, S.; Zhang, X.; Thureau, A.; Lescop, E.. Revisiting the Molecular Interactions Between the Tumor Protein TCTP and the Drugs Sertraline/thioridazine.. ChemMedChem 2022. doi:10.1002/cmdc.202100528
  • [DOI] Liu, D.; Peyre, F.; Loissell-Baltazar, Y.; Courilleau, D.; Lacas-Gervais, S.; Nicolas, V.; Jacquet, E.; Dokudovskaya, S.; Taran, F.; Cintrat, J.-C.; Brenner, C.. Identification of Small Molecules Inhibiting Cardiomyocyte Necrosis and Apoptosis by Autophagy Induction and Metabolism Reprogramming. Cells 2022, 11 (3), 474. doi:10.3390/cells11030474

2021

  • [DOI] Grimbert, L.; Sanz, M.-N.; Gressette, M.; Rucker-Martin, C.; Novotova, M.; Solgadi, A.; Karoui, A.; Gomez, S.; Bedouet, K.; Jacquet, E.; Lemaire, C.; Veksler, V.; Mericskay, M.; Ventura-Clapier, R.; Piquereau, J.; Garnier, A.. Spatiotemporal AMPK Α2 Deletion in Mice Induces Cardiac Dysfunction, Fibrosis and Cardiolipin Remodeling Associated with Mitochondrial Dysfunction in Males Only. Biology of Sex Differences 2021, 12 (1). doi:10.1186/s13293-021-00394-z
  • [DOI] Labarde, A.; Jakutyte, L.; Billaudeau, C.; Fauler, B.; López-Sanz, M.; Ponien, P.; Jacquet, E.; Mielke, T.; Ayora, S.; Carballido-López, R.; Tavares, P.. Temporal Compartmentalization of Viral Infection in Bacterial Cells. Proceedings of the National Academy of Sciences 2021, 118 (28), e2018297118. doi:10.1073/pnas.2018297118
  • [DOI] Garnier, A.; Bork, N.; Jacquet, E.; Zipfel, S.; Muñoz-Guijosa, C.; Baczkó, I.; Reichenspurner, H.; Donzeau-Gouge, P.; Maier, L.; Dobrev, D.; Girdauskas, E.; Nikolaev, V.; Fischmeister, R.; Molina, C.. Mapping Genetic Changes in the cAMP -signaling Cascade in Human Atria. Journal of Molecular and Cellular Cardiology 2021, 155, 10–20. doi:10.1016/j.yjmcc.2021.02.006
  • [DOI] Shikura, N.; Darbon, E.; Esnault, C.; Deniset-Besseau, A.; Xu, D.; Lejeune, C.; Jacquet, E.; Nhiri, N.; Sago, L.; Cornu, D.; Werten, S.; Martel, C.; Virolle, M.-J.. The Phosin PptA Plays a Negative Role in the Regulation of Antibiotic Production in Streptomyces Lividans. Antibiotics 2021, 10 (3), 325. doi:10.3390/antibiotics10030325
  • [DOI] Condamina, M.; Penso, L.; Tran, V.-T.; Hotz, C.; Guillem, P.; Villani, A.; Perrot, P.; Bru, M.-F.; Jacquet, E.; Nassif, A.; Bachelez, H.; Wolkenstein, P.; Beylot-Barry, M.; Richard, M.-A.; Ravaud, P.; Viguier, M.; Sbidian, E.. Baseline Characteristics of a National French E-cohort of Hidradenitis Suppurativa in ComPaRe and Comparison with Other Large Hidradenitis Suppurativa Cohorts. Dermatology 2021, 237 (5), 748–758. doi:10.1159/000513447

2020

  • [DOI] Chevreuil, M.; Lecoq, L.; Wang, S.; Gargowitsch, L.; Nhiri, N.; Jacquet, E.; Zinn, T.; Fieulaine, S.; Bressanelli, S.; Tresset, G.. Nonsymmetrical Dynamics of the HBV Capsid Assembly and Disassembly Evidenced by Their Transient Species. The Journal of Physical Chemistry B 2020, 124 (45), 9987–9995. doi:10.1021/acs.jpcb.0c05024
  • [DOI] Munoz-Montesino, C.; Larkem, D.; Barbereau, C.; Igel-Egalon, A.; Truchet, S.; Jacquet, E.; Nhiri, N.; Moudjou, M.; Sizun, C.; Rezaei, H.; Béringue, V.; Dron, M.. A Seven-residue Deletion in PrP Leads to Generation of a Spontaneous Prion Formed from C-terminal C1 Fragment of PrP. Journal of Biological Chemistry 2020, 295 (41), 14025–14039. doi:10.1074/jbc.ra120.014738
  • [DOI] Rivière, G.; Oueslati, S.; Gayral, M.; Créchet, J.-B.; Nhiri, N.; Jacquet, E.; Cintrat, J.-C.; Giraud, F.; Heijenoort, C.; Lescop, E.; Pethe, S.; Iorga, B.; Naas, T.; Guittet, E.; Morellet, N.. NMR Characterization of the Influence of Zinc( II ) Ions on the Structural and Dynamic Behavior of the New Delhi Metallo-β-lactamase-1 and on the Binding with Flavonols as Inhibitors. ACS Omega 2020, 5 (18), 10466–10480. doi:10.1021/acsomega.0c00590

2019

  • [DOI] Grima, B.; Papin, C.; Martin, B.; Chelot, E.; Ponien, P.; Jacquet, E.; Rouyer, F.. Period-controlled Deadenylation of the Timeless Transcript in the Drosophila Circadian Clock. Proc Natl Acad Sci U S A 2019, 116 (12), 5721–5726. doi:10.1073/pnas.1814418116
  • [DOI] Jais, P.; Decroly, E.; Jacquet, E.; Boulch, M.; Jais, A.; Jean-Jean, O.; Eaton, H.; Ponien, P.; Verdier, F.; Canard, B.; Goncalves, S.; Chiron, S.; Gall, M.; Mayeux, P.; Shmulevitz, M.. C3P3-G1: First Generation of a Eukaryotic Artificial Cytoplasmic Expression System. Nucleic Acids Res 2019, 47 (5), 2681–2698. doi:10.1093/nar/gkz069
  • [DOI] Petitalot, A.; Dardillac, E.; Jacquet, E.; Nhiri, N.; Guirouilh-Barbat, J.; Julien, P.; Bouazzaoui, I.; Bonte, D.; Feunteun, J.; Schnell, J.; Lafitte, P.; Aude, J.-C.; Nogues, C.; Rouleau, E.; Lidereau, R.; Lopez, B.; Zinn-Justin, S.; Caputo, S.; network, U.. Combining Homologous Recombination and Phosphopeptide-binding Data to Predict the Impact of BRCA1 BRCT Variants on Cancer Risk. Molecular cancer research : MCR 2019, 17 (1), 54–69. doi:10.1158/1541-7786.MCR-17-0357

2018

  • [DOI] Samra, A.; Robert, A.; Gov, C.; Favre, L.; Eloy, L.; Jacquet, E.; Bignon, J.; Wiels, J.; Desrat, S.; Roussi, F.. Dual Inhibitors of the Pro-survival Proteins Bcl-2 and Mcl-1 Derived from Natural Compound Meiogynin A. European Journal of Medicinal Chemistry 2018, 148, 26–38. doi:10.1016/j.ejmech.2018.01.100
  • [DOI] Gicquel, M.; Gomez, C.; Alvarez, M.; Pamlard, O.; Guerineau, V.; Jacquet, E.; Bignon, J.; Voituriez, A.; Marinetti, A.. Inhibition of P53-murine Double Minute 2 (MDM2) Interactions with 3,3'-spirocyclopentene Oxindole Derivatives. Journal of medicinal chemistry 2018, 61 (20), 9386–9392. doi:10.1021/acs.jmedchem.8b01137
  • [DOI] Grzela, R.; Nusbaum, J.; Fieulaine, S.; Lavecchia, F.; Desmadril, M.; Nhiri, N.; Dorsselaer, A.; Cianferani, S.; Jacquet, E.; Meinnel, T.; Giglione, C.. Peptide Deformylases from Vibrio Parahaemolyticus Phage and Bacteria Display Similar Deformylase Activity and Inhibitor Binding Clefts. Biochimica Et Biophysica Acta-Proteins and Proteomics 2018, 1866 (2), 348–355. doi:10.1016/j.bbapap.2017.10.007
  • [DOI] Molina, C.; Jacquet, E.; Ponien, P.; Munoz-Guijosa, C.; Baczko, I.; Maier, L.; Donzeau-Gouge, P.; Dobrev, D.; Fischmeister, R.; Garnier, A.. Identification of Optimal Reference Genes for Transcriptomic Analyses in Normal and Diseased Human Heart. Cardiovascular Research 2018, 114 (2), 247–258. doi:10.1093/cvr/cvx182
  • [DOI] Rochat, T.; Bohn, C.; Morvan, C.; Lam, T.; Razvi, F.; Pain, A.; Toffano-Nioche, C.; Ponien, P.; Jacq, A.; Jacquet, E.; Fey, P.; Gautheret, D.; Bouloc, P.. The Conserved Regulatory RNA Rsae Down-regulates the Arginine Degradation Pathway in Staphylococcus Aureus. Nucleic acids research 2018, 46 (17), 8803–8816. doi:10.1093/nar/gky584
  • [DOI] Samson, C.; Petitalot, A.; Celli, F.; Herrada, I.; Ropars, V.; Du, M.-H.; Nhiri, N.; Jacquet, E.; Arteni, A.-A.; Buendia, B.; Zinn-Justin, S.. Structural Analysis of the Ternary Complex Between Lamin A/C, BAF and Emerin Identifies an Interface Disrupted in Autosomal Recessive Progeroid Diseases. Nucleic acids research 2018, 46 (19), 10460–10473. doi:10.1093/nar/gky736

Quantitative PCR Plateform

Manager : Eric Jacquet (01 69 82 46 24)
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