CV M.-P. Golinelli

  • 2013-present : CNRS research associate at Institut de Chimie des Substances Naturelles – CNRS-Université Paris-Saclay
  • 2011-2013 : CNRS research associate at Institut Jacques Monod – CNRS-Université Paris Diderot
  • 2007 : Habilitation à Diriger ds Recherches
  • 2001 – 2011 : CNRS research associate at Laboratoire d’Enzymologie et Biochimie Structurales – CNRS-Université Paris-Saclay
  • 1999 – 2001 : Post-doctoral Fellow at the National Cancer Institute, National Institutes of Health, Frederick, USA with Dr Steve Hughes
  • 1997 – 1999 : Post-doctoral Fellow at University of Utah, Salt Lake City, USA  with Pr Sheila David
  • 1994-1997 : Ph.D. student at the Department of Molecular and Structural Biology, CEA, Grenoble, France with Dr Jacques Meyer

Fe-S proteins

Redox signaling and stress

Protein biochemistry and cellular biology

36 publications – 2 book chapters

15 oral communications and conferences, 30 poster communications

Complete list

1- I. Ferecatu, S. Gonçalves, M.-P. Golinelli-Cohen, M. Clémancey, A. Martelli, S. Riquier, E. Guittet, J.-M. Latour, H. Puccio, J.-C. Drapier, E. Lescop, C. Bouton. The Diabetes Drug Target MitoNEET Governs a Novel Trafficking Pathway to Rebuild an Fe-S Cluster into Cytosolic Aconitase/Iron Regulatory Protein 1. J. Biol. Chem. (2014) 289, 28070-28086. DOI: 10.1074/jbc.M114.548438.

2- A. Lalève , C. Vallières, M.-P. Golinelli-Cohen, C. Bouton, Z. Song, G. Pawlik, S. M. Tindall, S. V. Avery, J. Clain, B. Meunier. Studying the mode of action of the antimalarial drug primaquine in yeast. Redox Biology (2016) 7, 21-29. DOI: 10.1016/j.redox.2015.10.008.

3-  M.-P. Golinelli-Cohen*#, E. Lescop*, C. Mons, S. Goncalves, M. Clemancey, J. Santolini, E. Guittet, G. Blondin , J.-M. Latour, C. Bouton#. Redox Control of the Human Iron-Sulfur Repair Protein MitoNEET Activity via its Iron-Sulfur Cluster. J. Biol. Chem. (2016) 291, 7583-7593. (* co-premier auteurs)(# co-corresponding authors). DOI: 10.1074/jbc.M115.711218.

4-    A. Alexis, M. Antonini, M.-P. Golinelli-Cohen. Lien entre la protéine suppresseur de tumeur p53 et la biogenèse des protéines. Médecine/Sciences (2016) 32, 580-582. DOI: 10.1051/medsci/20163208014

5-  M.-P. Golinelli-Cohen# et C. Bouton#. Fe-S proteins acting as redox switch : new key actors of cellular adaptive responses. Curr. Chem. Biol (2017) (# co-corresponding authors) 11, 70-88. (revue) DOI: 10.2174/2212796811666170406163809.

5- E. Lebigot, P. Gaignard, I. Dorboz, A. Slama, M. Rio, P. de Lonlay, B. Héron, F. Sabourdy, O. Boespflug-Tanguy, A. Cardoso, F. Habarou, C. Ottolenghi, P. Thérond, C. Bouton, M.-P. Golinelli-Cohen, A. Boutron. Impact of mutations within the [Fe-S] cluster or the lipoic acid biosynthesis pathways on mitochondrial protein expression profiles in fibroblasts from patients. Mol. Genet. Metab. (2017) 122, 85-94. DOI: 10.1016/j.ymgme.2017.08.001.

6-    A. Carreaux, S. de Champs de Saint-Leger, Y. Kouidri, M.-P. Golinelli-Cohen. Contrôle de la virulence de Salmonella enterica par la machinerie de biogenèse des centres Fe-S. Médecine/Sciences (2017) 33, 603-606.  DOI : 10.1051/medsci/20173306015.

7- I. Ferecatu, F. Canal, L. Fabbri, N. Mazure, C. Bouton#, M.-P. Golinelli-Cohen#. Dysfunction in the mitochondrial Fe-S assembly machinery leads to the formation of the chemoresistant truncated VDAC1 isoform without HIF1-α activation. PloS One (2018) 13, e0194782. (# co-corresponding authors). DOI: 10.1371/journal.pone.0194782.

8- C. Mons, T. Botzanowski, A. Nikolaev, P. Hellwig, S. Cianférani, E. Lescop, C. Bouton, M.-P. Golinelli-Cohen. The H2O2-resistant Fe-S redox switch mitoNEET acts as a pH sensor to repair stress-damaged Fe-S protein. Biochemistry (2018) 57, 5616-5628. DOI: 10.1021/acs.biochem.8b00777.

9-    J. Guitton, M. Bekara, M.-P. Golinelli-Cohen, Les protéines Fe-S Wbl, de nouvelles cibles thérapeutiques pour lutter contre la tuberculose. Médecine/Sciences (2018) 34, 612-614.  DOI: 10.1051/medsci/20183406026.

Pr J.-J. Benoliel-Dr C. Becker (Paris V)

Dr S. Cianferani (UNISTRA, France)

Pr. S. Cramer (USA)

Dr P. Dorlet (Marseille, France)

Pr S. Gil-Dr I. Ferecatu (Paris V)

Pr P. Hellwig (UNISTRA, France)

Dr B. Meunier (I2BC, France)

Dr

CNRS Research Associate
(ORCID)

ICSN-CNRS Bât. 27

1, avenue de la Terrasse

91190 Gif-sur-Yvette France

marie-pierre.golinelli_at_cnrs.fr

+33 1 69 82 45 82