2022

  • [DOI] Ma, W.-Y.; Montinho-Inacio, E.; Iorga, B.; Retailleau, P.; Moreau, X.; Neuville, L.; Masson, G.. Chiral Phosphoric Acid-catalyzed Enantioselective Formal [4+2] Cycloaddition Between Dienecarbamates and 2-benzothioazolimines. Advanced Synthesis & Catalysis 2022, 364 (10), 1708–1715. doi:10.1002/adsc.202200161

2021

  • [DOI] Gatin-Fraudet, B.; Ottenwelter, R.; Saux, T.; Norsikian, S.; Pucher, M.; Lombès, T.; Baron, A.; Durand, P.; Doisneau, G.; Bourdreux, Y.; Iorga, B.; Erard, M.; Jullien, L.; Guianvarc'h, D.; Urban, D.; Vauzeilles, B.. Evaluation of Borinic Acids as New, Fast Hydrogen Peroxide – Responsive Triggers. Proceedings of the National Academy of Sciences 2021, 118 (50), e2107503118. doi:10.1073/pnas.2107503118
  • [DOI] Juillet, C.; Ermolenko, L.; Boyarskaya, D.; Baratte, B.; Josselin, B.; Nedev, H.; Bach, S.; Iorga, B.; Bignon, J.; Ruchaud, S.; Al-Mourabit, A.. From Synthetic Simplified Marine Metabolite Analogues to New Selective Allosteric Inhibitor of Aurora B Kinase. Journal of Medicinal Chemistry 2021, 64 (2), 1197–1219. doi:10.1021/acs.jmedchem.0c02064

2020

  • [DOI] Benchekroun, M.; Ermolenko, L.; Tran, M.; Vagneux, A.; Nedev, H.; Delehouzé, C.; Souab, M.; Baratte, B.; Josselin, B.; Iorga, B.; Ruchaud, S.; Bach, S.; Al-Mourabit, A.. Discovery of Simplified Benzazole Fragments Derived from the Marine Benzosceptrin B as Necroptosis Inhibitors Involving the Receptor Interacting Protein Kinase-1. European Journal of Medicinal Chemistry 2020, 201, 112337. doi:10.1016/j.ejmech.2020.112337

2019

  • [DOI] Dallery, J.; Goff, G.; Adelin, E.; Iorga, B.; Pigne, S.; O'Connell, R.; Ouazzani, J.. Deleting a Chromatin Remodeling Gene Increases the Diversity of Secondary Metabolites Produced by Colletotrichum Higginsianum. J Nat Prod 2019, 82 (4), 813–822. doi:10.1021/acs.jnatprod.8b00796

Responsable : Bogdan Iorga (01 69 82 30 94)

Ingénieur plateforme : Hristo Nedev (01 69 82 45 79)