CV S. Vidal

2019-now
CNRS research director DR2, Institut de Chimie des Substances Naturelles UPR-CNRS 2301, Gif-sur-Yvette, France.
2015-2019 CNRS research director DR2, Université Claude Bernard Lyon 1, UMR-CNRS 5246, Lyon, France.
2008-2015 CNRS researcher CR1, Université Claude Bernard Lyon 1, UMR-CNRS 5246, Lyon, France.
2007 HDR diploma (habilitation to conduct research). Jury : Dr. Yves Queneau, Dr. Jean-Pierre Praly, Prof. Jean-Marc Lancelin, Dr Anne Imberty, Prof. Jean-Marie Beau, Prof. Pascal Dumy, Prof. René Roy.
2004-2008 CNRS researcher CR2, Université Claude Bernard Lyon 1, UMR-CNRS 5246, Lyon, France.
2004 Post-doctoral Fellow at Université Claude Bernard Lyon 1, UMR-CNRS 5246 (Lyon, France, Prof. Peter G. Goekjian ).
2003-2004 Post-doctoral Fellow at National Renewable Energy Laboratory (NREL), Golden, Etats-Unis, Prof. Joseph Bozell ).
2000-2003 Post-doctoral Fellow at University of California at Los Angeles (UCLA, Los Angeles, Etats-Unis, Prof. J. Fraser Stoddart ).
1997-2000 PhD at Laboratoire de Chimie Biomoléculaire (UMR-CNRS 5247, Montpellier, France) under the supervizion of Prof. Jean-Louis Montero

Organic Chemistry

Glycochimistry

Supramolecular Chemistry

Ligand-receptor interactions

«Click chemistry»

Dynamic Combinatory  Chemistry

Multivalence

Lectines

101 Articles, 5 patents, 
13 Book Chapters, 3 Edited Books
28 Oral presentations (5 as invited speaker)

  1. Ghannay, S.; Bakari, S.; Msaddek, M.; Vidal, S.; Kadri, A.; Aouadi, K. « Design, synthesis, molecular properties and in vitro antioxidant and antibacterial potential of novel enantiopure isoxazolidine derivatives »Arabian J. Chem. 2020, 13, 2121-2131.
  2. Pommier, M.; Vidal, S. « Anomeric Spiro-Annulated Glycopyranosides: An Overview of Synthetic Methodologies and Biological Applications »Top. Heterocycl. Chem. 2019, 57, 1-25.
  3. Dong, L.; Chen, G.-R.; He, X.-P.; Vidal, S. »Thiophenol detection using an AIE fluorescent probe through self-assembly with TPE-based glycoclusters » Org. Biomol. Chem. 2019, 17, 9251–9256.
  4. Zuttion, F.; Sicard, D.; Dupin, L.; Vergoten, G.; Girard-Bock, C.; Madaoui, M.; Chevolot, Y.; Morvan, F.; Vidal, S.; Vasseur, J.-J.; Souteyrand, E.; Phaner-Goutorbe, M. « Deciphering multivalent glycocluster–lectin interactions through AFM characterization of the self-assembled nanostructures » Soft Matter 2019, 15, 7211–7218.
  5. Faltinek, L.; Fujdiarová, E.; Melicher, F.; Houser, J.; Kašáková, M.; Kondakov, N.; Kononov, L.; Parkan, K.; Vidal, S.; Wimmerová, M. « Lectin PLL3, a Novel Monomeric Member of the Seven-Bladed β-Propeller Lectin Family »Molecules 2019, 24, 4540.
  6. Donnier-Maréchal, M.; Abdullayev, S.; Bauduin, M.; Pascal, Y.; Fu, M.-Q.; He, X.-P.; Gillon, E.; Imberty, A.; Kipnis, E.; Dessein, R.; Vidal, S. »Tetraphenylethylene-based glycoclusters with aggregation-induced emission (AIE) properties as high-affinity ligands of bacterial lectins » Org. Biomol. Chem. 2018, 16, 8804-8809.
  7. Zuttion, F.; Ligeour, C.; Vidal, O.; Walte, M.; Morvan, F.; Vidal, S.; Vasseur, J.-J.; Chevolot, Y.; Phaner-Goutorbe, M.; Schillers, H. « The anti-adhesive effect of glycoclusters on Pseudomonas aeruginosa bacteria adhesion to epithelial cells studied by AFM single cell force spectroscopy » Nanoscale 2018, 10, 12771-12778.
  8. Matthews, S. E.; Cecioni, S.; O’Brien, J. E.; MacDonald, C. J.; Hughes, D. L.; Jones, G. A.; Ashworth, S. H.; Vidal, S. « Fixing the Conformation of Calix[4]arenes: When Are Three Carbons Not Enough? » Chem. Eur. J. 2018, 24, 4436–4444.
  9. Thorsheim, K.; Willén, D.; Tykesson, E.; Ståhle, J.; Praly, J.-P.; Vidal, S.; Johnson, M. T.; Widmalm, G.; Manner, S.; Ellervik, U. « Naphthyl Thio- and Carba-xylopyranosides for Exploration of the Active Site of β-1,4-Galactosyltransferase 7 (β4GalT7) » Chem. Eur. J. 2017, 23, 18057–18065.
  10. Donnier-Maréchal, M.; Galanos, N.; Grandjean, T.; Pascal, Y.; Ji, D.-K.; Dong, L.; Gillon, E.; He, X.-P.; Imberty, A.; Kipnis, E.; Dessein, R.; Vidal, S. « Perylenediimide-based glycoclusters as high affinity ligands of bacterial lectins: synthesis, binding studies and anti-adhesive properties » Org. Biomol. Chem. 2017, 15, 10037–10043.
  11. Angeli, A.; Dupin, L.; Madaoui, M.; Li, M.; Vergoten, G.; Wang, S.; Meyer, A.; Géhin, T.; Vidal, S.; Vasseur, J.-J.; Chevolot, Y.; Morvan, F. « Glycoclusters with Additional Functionalities for Binding to the LecA Lectin from Pseudomonas aeruginosa » ChemistrySelect 2017, 2, 10420–10427.
  12. Liu, Y.; Ji, D.-K.; Dong, L.; Galanos, N.; Zang, Y.; Li, J.; Vidal, S.; He, X.-P. « Supramolecular assembly of fluorogenic glyco-dots from perylenediimide-based glycoclusters for targeted imaging of cancer cells » Chem. Commun. 2017, 53, 11937–11940.
  13. Angeli, A.; Li, M.; Dupin, L.; Vergoten, G.; Noël, M.; Madaoui, M.; Wang, S.; Meyer, A.; Géhin, T.; Vidal, S.; Vasseur, J.-J.; Chevolot, Y.; Morvan, F. « Design and Synthesis of Galactosylated Bifurcated Ligands with Nanomolar Affinity for Lectin LecA from Pseudomonas aeruginosa » ChemBioChem 2017, 18, 1036–1047.
  14. Bokor, É.; Kun, S.; Goyard, D.; Tóth, M.; Praly, J.-P.; Vidal, S.; Somsák, L. « C-Glycopyranosyl Arenes and Hetarenes: Synthetic Methods and Bioactivity Focused on Antidiabetic Potential » Chem. Rev. 2017, 117, 1687–1764.
  15. Brahmi, J.; Ghannay, S.; Bakari, S.; Aouadi, K.; Kadri, A.; Msaddek, M.; Vidal, S. « Unprecedented stereoselective synthesis of 3-methylisoxazolidine-5-aryl-1,2,4-oxadiazoles via 1,3-dipolar cycloaddition and study of their in vitro antioxidant activity » Synth. Commun. 2016, 46, 2037–2044.
  16. Galanos, N.; Chen, Y.; Michael, Z. P.; Gillon, E.; Dutasta, J.-P.; Star, A.; Imberty, A.; Martinez, A.; Vidal, S. « Cyclotriveratrylene-Based Glycoclusters as High Affinity Ligands of Bacterial Lectins from Pseudomonas aeruginosa and Burkholderia ambifaria » ChemistrySelect 2016, 1, 5863–5868.
  17. Abda, H.; Aouadi, K.; Mssadek, M.; Vidal, S. »Synthesis of some isoxazolidine and isoxazoline derivatives using nitrone-derived (‒)-menthone via 1,3-dipolar cycloaddition with alkenes, alkynes, and cycloalkenes » Heterocycles 2016, 92, 1963–1975.
  18. Brahmi, J.; Aouadi, K.; Msaddek, M.; Praly, J.-P.; Vidal, S. « A stereoselective method for the synthesis of enantiopure 3-substituted 4-hydroxyproline derivatives via 1,3-dipolar cycloadditions » C. R. Chimie 2016, 19, 933–935.
  19. Wang, S.; Dupin, L.; Noël, M.; Carroux, C. J.; Renaud, L.; Géhin, T.; Meyer, A.; Souteyrand, E.; Vasseur, J.-J.; Vergoten, G.; Chevolot, Y.; Morvan, F.; Vidal, S. « Toward the Rational Design of Galactosylated Glycoclusters That Target Pseudomonas aeruginosa Lectin A (LecA): Influence of Linker Arms That Lead to Low-Nanomolar Multivalent Ligands » Chem. Eur. J. 2016, 22, 11785–11794.
  20. Boukerb, A. M.; Decor, A.; Ribun, S.; Tabaroni, R.; Rousset, A.; Commin, L.; Buff, S.; Doleans-Jordheim, A.; Vidal, S.; Varrot, A.; Imberty, A.; Cournoyer, B. « Genomic rearrangements and functional diversification of lecA and lecB lectin-coding regions impacting the efficacy of glycomimetics directed against Pseudomonas aeruginosa » Front. Microbiol. 2016, 7, 811.
  21. Abda, H.; Aouadi, K.; Brahmi, J.; Msaddek, M.; Vidal, S. « Unexpected synthesis of aziridines under Cu(I) catalyzed Kinugasa conditions assisted by microwave irradiation » C. R. Chimie 2016, 19, 274–277.
  22. Galanos, N.; Gillon, E.; Imberty, A.; Matthews, S. E.; Vidal, S. « Pentavalent pillar[5]arene-based glycoclusters and their multivalent binding to pathogenic bacterial lectins » Org. Biomol. Chem. 2016, 14, 3476–3481.
  23. Brahmi, J.; Nasri, S.; Aouadi, K.; Jeanneau, E.; Vidal, S.; Msaddek, M. »Crystal structure of 5-chloromethyl-N-methyl-4-[(4-phenyl-1,2,3-triazol-1-yl)methyl]isoxazolidine-3-carboxamide » Acta Cryst. 2016, E72, 378–381.
  24. Buffet, K.; Nierengarten, I.; Galanos, N.; Gillon, E.; Holler, M.; Imberty, A.; Matthews, S. E.; Vidal, S.; Vincent, S. P.; Nierengarten, J.-F. « Pillar[5]arene-Based Glycoclusters: Synthesis and Multivalent Binding to Pathogenic Bacterial Lectins » Chem. Eur. J. 2016, 22, 2955–2963.
  25. Donnier-Maréchal, M.; Vidal, S. « Glycogen phosphorylase inhibitors: a patent review (2013-2015) » Exp. Opin. Ther. Patents 2016, 26, 199–212.
  26. Vidal, S. « Glycofullerenes: Sweet fullerenes vanquish viruses » Nat. Chem. 2016, 8, 4–6. (News & Views)
  27. Goyard, D.; Kónya, B.; Chajistamatiou, A. S.; Chrysina, E. D.; Leroy, J.; Balzarin, S.; Tournier, M.; Tousch, D.; Petit, P.; Duret, C.; Maurel, P.; Somsák, L.; Docsa, T.; Gergely, P.; Praly, J.-P.; Azay-Milhau, J.; Vidal, S. « Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition » Eur. J. Med. Chem. 2016, 108, 444–454.
  28. Ligeour, C.; Dupin, L.; Angeli, A.; Vergoten, G.; Vidal, S.; Meyer, A.; Souteyrand, E.; Vasseur, J.-J.; Chevolot, Y.; Morvan, F. « Importance of topology for glycocluster binding to Pseudomonas aeruginosa and Burkholderia ambifaria bacterial lectins » Org. Biomol. Chem. 2015, 13, 11244–11254.
  29. Wang, S.; Cuesta-Seijo, J. A.; Striebeck, A.; Lafont, D.; Palcic, M. M.; Vidal, S. « Design of Glycosyltransferase Inhibitors: Serine Analogues as Pyrophosphate Surrogates? » ChemPlusChem 2015, 80, 1525–1532.
  30. Ligeour, C.; Vidal, O.; Dupin, L.; Casoni, F.; Gillon, E.; Meyer, A.; Vidal, S.; Vergoten, G.; Lacroix, J.-M.; Souteyrand, E.; Imberty, A.; Vasseur, J.-J.; Chevolot, Y.; Morvan, F. « Mannose-centered aromatic galactoclusters inhibit the biofilm formation of Pseudomonas aeruginosa » Org. Biomol. Chem. 2015, 13, 8433–8444.
  31. Donnier-Maréchal, M.; Goyard, D.; Folliard, V.; Docsa, T.; Gergely, P.; Praly, J.-P.; Vidal, S. “3-Glucosylated 5-amino-1,2,4-oxadiazoles: synthesis and evaluation as glycogen phosphorylase inhibitors » Beilstein J. Org. Chem. 2015, 11, 499–503.
  32. Cecioni, S.; Imberty, A.; Vidal, S. « Glycomimetics versus Multivalent Glycoconjugates for the Design of High Affinity Lectin Ligands » Chem. Rev. 2015, 115, 525–561.
  33. Goyard, D.; Docsa, T.; Gergely, P.; Praly, J.-P.; Vidal, S. « Synthesis of 4-amidomethyl-1-glucosyl-1,2,3-triazoles and evaluation as glycogen phosphorylase inhibitors » Carbohydr. Res. 2015, 402, 245–251.
  34. Boukerb, A. M.; Rousset, A.; Galanos, N.; Méar, J.-B.; Grandjean, T.; Gillon, E.; Cecioni, S.; Abderrahmen, C.; Faure, K.; Redelberger, D.; Kipnis, E.; Dessein, R.; Havet, S.; Darblade, B.; Matthews, S. E.; de Bentzmann, S.; Guéry, B.; Cournoyer, B.; Imberty, A.; Vidal, S. « Anti-adhesive properties of glycoclusters against Pseudomonas aeruginosa lung infection » J. Med. Chem. 2014, 57, 10275–10289.
  35. Abda, H.; Aouadi, K.; Perrin, L.; Msaddek, M.; Praly, J.-P.; Vidal, S. « Stereoselective Synthesis of Enantiopure Cycloalkylglycines by 1,3-Dipolar Cycloaddition of a Chiral Nitrone to Cycloalkenes » Eur. J. Org. Chem. 2014, 6017–6024.
  36. Wang, S.; Shen, D. L.; Lafont, D.; Vercoutter-Edouart, A.-S.; Mortuaire, M.; Shi, Y.; Maniti, O.; Girard-Egrot, A.; Lefebvre, T.; Pinto, B. M.; Vocadlo, D.; Vidal, S. « Design of glycosyltransferase inhibitors targeting human O-GlcNAc transferase (OGT) » Med. Chem. Commun. 2014, 5, 1172–1178.
  37. Wang, S.; Galanos, N.; Rousset, A.; Buffet, K.; Cecioni, S.; Lafont, D.; Vincent, S. P.; Vidal, S. “Fucosylation of triethyleneglycol-based acceptors into « clickable » a-fucosides » Carbohydr. Res. 2014, 395, 15–18.
  38. Goyard, D.; Chajistamatiou, A. S.; Sotiropoulou, A. I.; Chrysina, E. D.; Praly, J.-P.; Vidal, S. “Efficient Atropodiastereoselective Access to 5,5’-Bis-1,2,3-triazoles: Studies on 1-Glucosylated 5-Halogeno 1,2,3-Triazoles and Their 5-Substituted Derivatives as Glycogen Phosphorylase Inhibitors » Chem. Eur. J. 2014, 20, 5423–5432.
  39. Gerland, B.; Goudot, A.; Ligeour, C.; Pourceau, G.; Meyer, A.; Vidal, S.; Gehin, T.; Vidal, O.; Souteyrand, E.; Vasseur, J.-J.; Chevolot, Y.; Morvan, F. « Structure Binding Relationship of Galactosylated Glycoclusters toward Pseudomonas aeruginosa Lectin LecA Using a DNA-Based Carbohydrate Microarray » Bioconjugate Chem. 2014, 25, 379–392.
  40. Brissonnet, Y.; Ortiz Mellet, C.; Morandat, S.; Garcia Moreno, M. I.; Deniaud, D.; Matthews, S. E.; Vidal, S.; Sestak, S.; El Kirat, K.; Gouin, S. G. « Topological Effects and Binding Modes Operating with Multivalent Iminosugar-Based Glycoclusters and Mannosidases » J. Am. Chem. Soc. 2013, 135, 18427–18435.
  41. Sicard, D.; Chevolot, Y.; Souteyrand, E.; Imberty, A.; Vidal, S.; Phaner-Goutorbe, M. “Molecular arrangement between multivalent glycocluster and Pseudomonas aeruginosa LecA (PA-IL) by atomic force microscopy: influence of the glycocluster concentration » J. Mol. Recognit. 2013, 26, 694–699.
  42. Wang, S.; Cuesta-Seijo, J. A.; Lafont, D.; Palcic, M. M.; Vidal, S. « Design of Glycosyltransferase Inhibitors: Pyridine as a Pyrophosphate Surrogate » Chem. Eur. J. 2013, 19, 15346–15357.
  43. Ligeour, C.; Audfray, A.; Gillon, E.; Meyer, A.; Galanos, N.; Vidal, S.; Vasseur, J.-J.; Imberty, A.; Morvan, F. « Synthesis of branched-phosphodiester and mannose-centered fucosylated glycoclusters and their binding studies with Burkholderia ambifaria lectin (BambL) » RSC Adv. 2013, 3, 19515–19524.
  44. Gening, M. L.; Tsvetkov, Y. E.; Titov, D. V.; Gerbst, A. G.; Yudina, O. N.; Grachev, A. A.; Shashkov, A. S.; Vidal, S.; Imberty, A.; Saha, T.; Kand, D.; Talukdar, P.; Pier, G. B.; Nifantiev, N. E. « Linear and cyclic oligo-β-(1→6)-D-glucosamines: Synthesis, conformations, and applications for design of a vaccine and oligodentate glycoconjugates » Pure Appl. Chem. 2013, 85, 1879–1891.
  45. Gening, M. L.; Titov, D. V.; Cecioni, S.; Audfray, A.; Gerbst, A. G.; Tsvetkov, Y. E.; Krylov, V. B.; Imberty, A.; Nifantiev, N. E.; Vidal, S. « Synthesis of Multivalent Carbohydrate-Centered Glycoclusters as Nanomolar Ligands of the Bacterial Lectin LecA from Pseudomonas aeruginosa » Chem. Eur. J. 2013, 19, 9272–9285.
  46. Wang, S.; Lafont, D.; Rahkila, J.; Picod, B.; Leino, R.; Vidal, S. « Glycosylation of « basic » alcohols: methyl 6-(hydroxymethyl)picolinate as a case study » Carbohydr. Res. 2013, 372, 35–46.
  47. Aouadi, K.; Vidal, S.; Msaddek, M.; Praly, J.-P. « Stereoselective synthesis of 1,2,3-triazolyl-functionalized isoxazolidines, via two consecutive 1,3-dipolar cycloadditions, as precursors of unnatural amino acids » Tetrahedron Lett. 2013, 54, 1967–1971.
  48. Bernardi, A.; Jiménez-Barbero, J.; Casnati, A.; De Castro, C.; Darbre, T.; Fieschi, F.; Finne, J.; Funken, H.; Jaeger, K.-E.; Lahmann, M.; Lindhorst, T. K.; Marradi, M.; Messner, P.; Molinaro, A.; Murphy, P.; Nativi, C.; Oscarson, S.; Penadés, S.; Peri, F.; Pieters, R.; Renaudet, O.; Reymond, J.-L.; Richichi, B.; Rojo, J.; Sansone, F.; Schäffer, C.; Turnbull, B.; Velasco-Torrijos, T.; Vidal, S.; Vincent, S.; Wennekes, T.; Zuilhof, H.; Imberty, A. »Multivalent glycoconjugates as anti-pathogenic agents » Chem. Soc. Rev. 2013, 42, 4709–4727.
  49. Chen, Y.; Star, A.; Vidal, S. « Sweet carbon nanostructures: carbohydrate conjugates with carbon nanotubes and graphene and their applications » Chem. Soc. Rev. 2013, 42, 4532–4542.
  50. Goudot, A.; Pourceau, G.; Meyer, A.; Gehin, T.; Vidal, S.; Vasseur, J.-J.; Morvan, F.; Souteyrand, E.; Chevolot, Y. « Quantitative analysis (Kd and IC50) of glycoconjugates interactions with a bacterial lectin on a carbohydrate microarray with DNA Direct Immobilization (DDI) » Biosens. Bioelectron. 2013, 40, 153–160.
  51. Morvan, F.; Vidal, S.; Souteyrand, E.; Chevolot, Y.; Vasseur, J.-J. « DNA glycoclusters and DNA-based carbohydrate microarrays: From design to applications » RSC Advances 2012, 2, 12043–12068.
  52. Goyard, D.; Baron, M.; Skourti, P. V.; Chajistamatiou, A. S.; Docsa, T.; Gergely, P.; Chrysina, E. D.; Praly, J.-P.; Vidal, S. « Synthesis of 1,2,3-triazoles from xylosyl and 5-thioxylosyl azides: evaluation of the xylose scaffold for the design of potential glycogen phosphorylase inhibitors » Carbohydr. Res. 2012, 364, 28–40.
  53. Goyard, D.; Praly, J.-P.; Vidal, S. « Synthesis of 5-halogenated 1,2,3-triazoles under stoichiometric Cu(I)-mediated azide-alkyne cycloaddition (CuAAC or « Click Chemistry ») » Carbohydr. Res. 2012, 362, 79–83.
  54. Feuillastre, S.; Chajistamatiou, A. S.; Potamitis, C.; Zervou, M.; Zoumpoulakis, P.; Chrysina, E. D.; Praly, J.-P.; Vidal, S. « C-Glucosylated malonitrile as a key intermediate towards carbohydrate-based glycogen phosphorylase inhibitors » Bioorg. Med. Chem. 2012, 20, 5592–5599.
  55. Gerland, B.; Goudot, A.; Pourceau, G.; Meyer, A.; Vidal, S.; Souteyrand, E.; Vasseur, J.-J.; Chevolot, Y.; Morvan, F. « Synthesis of Homo- and Heterofunctionalized Glycoclusters and Binding to Pseudomonas aeruginosa Lectins PA-IL and PA-IIL » J. Org. Chem. 2012, 77, 7620–7626.
  56. Gerland, B.; Goudot, A.; Pourceau, G.; Meyer, A.; Dugas, V.; Cecioni, S.; Vidal, S.; Souteyrand, E.; Vasseur, J.-J.; Chevolot, Y.; Morvan, F. « Synthesis of a Library of Fucosylated Glycoclusters and Determination of their Binding toward Pseudomonas aeruginosa Lectin B (PA-IIL) Using a DNA-Based Carbohydrate Microarray » Bioconjugate Chem. 2012, 23, 1534–1547.
  57. Cecioni, S.; Praly, J.-P.; Matthews, S. E.; Wimmerová, M.; Imberty, A.; Vidal, S. « Rational Design and Synthesis of Optimized Glycoclusters for Multivalent Lectin-Carbohydrate Interactions: Influence of the Linker Arm » Chem. Eur. J. 2012, 18, 6250–6263.
  58. Cecioni, S.; Matthews, S. E.; Blanchard, H.; Praly, J.-P.; Imberty, A.; Vidal, S. « Synthesis of lactosylated glycoclusters and inhibition studies with plant and human lectins » Carbohydr. Res. 2012, 356, 132–141.
  59. Chen, Y.; Vedala, H.; Kotchey, G. P.; Audfray, A.; Cecioni, S.; Imberty, A.; Vidal, S.; Star, A. « Electronic Detection of Lectins Using Carbohydrate-Functionalized Nanostructures: Graphene versus Carbon Nanotubes » ACS Nano 2012, 6, 760–770.
  60. Soomro, Z. H.; Cecioni, S.; Blanchard, H.; Praly, J.-P.; Imberty, A.; Vidal S.; Matthews S. E. “CuAAC synthesis of resorcin[4]arene-based glycoclusters as multivalent ligands of lectins » Org. Biomol. Chem. 2011, 9, 6587–6597.
  61. Pourceau, G.; Chevolot, Y.; Goudot, A.; Giroux, F.; Meyer, A.; Moulés, V.; Lina, B.; Cecioni, S.; Vidal, S.; Yu, H.; Chen, X.; Ferraris, O.; Praly, J.-P.; Souteyrand, E.; Vasseur, J.-J.; Morvan, F. « Measurement of Enzymatic Activity and Specificity of Human and Avian Influenza Neuraminidases from Whole Virus by Glycoarray and MALDI-TOF Mass Spectrometry » ChemBioChem 2011, 12, 2071–2080.
  62. Sicard, D.; Cecioni, S.; Iazykov, M.; Chevolot, Y.; Matthews, S. E.; Praly, J.-P.; Souteyrand, E.; Imberty, A.; Vidal, S.; Phaner-Goutorbe, M. « AFM investigation of Pseudomonas aeruginosa lectin LecA (PA-IL) filaments induced by multivalent glycoclusters » Chem. Commun. 2011, 9483–9485.
  63. Chevolot, Y.; Zhang, J.; Meyer, A.; Goudot, A.; Rouanet, S.; Vidal, S.; Pourceau, G.; Cloarec, J.-P.; Praly, J.-P.; Souteyrand, E.; Vasseur, J.-J.; Morvan, F. « Multiplexed binding determination of seven glycoconjugates for Pseudomonas aeruginosa Lectin I (PA-IL) using a DNA-based carbohydrate microarray » Chem. Commun. 2011, 8826–8828.
  64. Cecioni, S.; Oerthel, V.; Iehl, J.; Holler, M.; Goyard, D.; Praly, J.-P.; Imberty, A.; Nierengarten, J.-F.; Vidal, S. « Synthesis of Dodecavalent Fullerene-Based Glycoclusters and Evaluation of Their Binding Properties towards a Bacterial Lectin » Chem. Eur. J. 2011, 17, 3252–3261.
  65. Cecioni, S.; Faure, S.; Darbost, U.; Bonnamour, I.; Parrot-Lopez, H.; Roy, O.; Taillefumier, C.; Wimmerová, M.; Praly, J.-P.; Imberty, A.; Vidal, S. « Selectivity among Two Lectins: Probing the Effect of Topology, Multivalency and Flexibility of “Clicked” Multivalent Glycoclusters » Chem. Eur. J. 2011, 17, 2146–2159.
  66. Vedala, H.; Chen, Y.; Cecioni, S.; Imberty, A.; Vidal, S.; Star, A. « Nanoelectronic Detection of Lectin-Carbohydrate Interactions Using Carbon Nanotubes » Nano Lett. 2011, 1, 170–175.
  67. Praly, J.-P.; Vidal, S. « Inhibition of Glycogen Phosphorylase in the Context of Type 2 Diabetes, with Focus on Recent Inhibitors Bound at the Active Site » Mini-Rev. Med. Chem. 2010, 10, 1102–1126.
  68. Nierengarten, J.-F.; Iehl, J.; Oerthel, V.; Holler, M.; Illescas, B.M.; Munoz, A.; Martin, N.; Rojo, J.; Sanchez-Navarro, M.; Cecioni, S.; Vidal, S.; Buffet, K.; Durka, M.; Vincent, S. P. « Fullerene sugar balls » Chem. Commun. 2010, 46, 3860–3862.
  69. Goyard, D.; Telligmann, S. M.; Goux-Henry, C.; Boysen, M. M. K.; Framery, E.; Gueyrard, D.; Vidal, S. « Carbohydrate-based spiro bis(isoxazolines): synthesis and evaluation in asymmetric catalysis » Tetrahedron Lett. 2010, 51, 374–377.
  70. Cecioni, S.; Lalor, R.; Blanchard, B.; Praly, J.-P.; Imberty, A.; Matthews, S.A.; Vidal, S. « Achieving High Affinity towards a Bacterial Lectin through Multivalent Topological Isomers of Calix[4]arene Glycoconjugates » Chem. Eur. J. 2009, 15, 13232–13240.
  71. Zhang, J.; Pourceau, G.; Meyer, A.; Vidal, S.; Praly, J.-P.; Souteyrand, E.; Vasseur, J.-J.; Morvan, F.; Chevolot, Y. « Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray » Chem. Commun. 2009, 6795–6797.
  72. Benltifa, M.; Hayes, J. M.; Vidal, S.; Gueyrard, D.; Goekjian, P.G.; Praly, J.-P.; Kizilis, G.; Tiraidis, C.; Alexacou, K.-M.; Chrysina, E.D.; Zographos, S.E.; Leonidas, D.D.; Archontis, G.; Oikonomakos, N.G. « Glucose-based spiro-isoxazolines: A new family of potent glycogen phosphorylase inhibitors » Bioorg. Med. Chem. 2009, 17, 7368–7380.
  73. Xue, J. L.; Cecioni, S.; He, L.; Vidal, S.; Praly, J.-P « Variations on the SnCl4 and CF3CO2Ag-promoted glycosidation of sugar acetates: a direct, versatile and apparently simple method with either a or b stereocontrol » Carbohydr. Res. 2009, 344, 1646–1653.
  74. Nagy, V.; Benltifa, M.; Vidal, S.; Berzsényi E.; Teilhet, C.; Czifrák, K.; Batta, G.; Docsa, T.; Gergely, P.; Somsák, L.; Praly, J.-P. « Glucose-based spiro-heterocycles as potent inhibitors of glycogen phosphorylase » Bioorg. Med. Chem. 2009, 17, 5696–5707.
  75. Tóth, M.; Kun, S.; Bokor, É; Benltifa, M.; Tallec, G.; Vidal, S.; Docsa, T.; Gergely, P.; Somsák, L.; Praly, J.-P. « Synthesis and structure–activity relationships of C-glycosylated oxadiazoles as inhibitors of glycogen phosphorylase » Bioorg. Med. Chem. 2009, 17, 4773–4785.
  76. Moni, L.; Pourceau, G.; Zhang, J.; Meyer, A.; Vidal, S.; Souteyrand, E.; Dondoni, A.; Morvan, F.; Chevolot, Y.; Vasseur, J.-J.; Marra, A. « Design of Triazole-Tethered Glycoclusters Exhibiting Three Different Spatial Arrangements and Comparative Study of their Affinities towards PA-IL and RCA 120 by Using a DNA-Based Glycoarray » ChemBioChem 2009, 10, 1369–1378.
  77. Zhang, J.; Pourceau, G.; Meyer, A.; Vidal, S.; Praly, J.-P.; Souteyrand, E.; Vasseur, J.-J.; Morvan, F.; Chevolot, Y. « DNA-directed immobilisation of glycomimetics for glycoarrays application: Comparison with covalent immobilisation, and development of an on-chip IC50 measurement assay » Biosens. Bioelectron. 2009, 24, 2515–2521.
  78. Cecioni, S.; Argintaru, O.-A.; Docsa, T.; Gergely, P.; Praly, J.-P.; Vidal, S. « Probing multivalency for the inhibition of an enzyme: glycogen phosphorylase as a case study » New J. Chem. 2009, 33, 148–156.
  79. Bozell, J.J.; Tice, N.C.; Sanyal, N.; Thompson, D.; Kim, J.-M.; Vidal, S. « Synthesis and self-assembly of glycal-based bolaforms » J. Org. Chem. 2008, 73, 8763–8771.
  80. Somsák, L; Nagy, V.; Vidal, S.; Czifrák, K; Berzsényi, E.; Praly, J.-P. « Novel design principle validated: Glucopyranosylidene-spiro-oxathiazole as new nanomolar inhibitor of glycogen phosphorylase, potential antidiabetic agent » Bioorg. Med. Chem. Lett. 2008, 18, 5680–5683.
  81. Bertus, P.; Szymoniak, J.; Jeanneau, E.; Docsa, T.; Gergely, P.; Praly, J.-P.; Vidal, S. « Synthesis of a C-glucosylated cyclopropylamide and evaluation as a glycogen phosphorylase inhibitor » Bioorg. Med. Chem. Lett. 2008, 18, 4774–4778.
  82. Morvan, F.; Meyer, A.; Jochum, A.; Sabin, C.; Chevolot, Y.; Imberty, A.; Praly, J.-P.; Vasseur, J.-J.; Souteyrand, E.; Vidal, S. « Fucosylated Pentaerythrityl Phosphodiester Oligomers (PePOs): Automated synthesis of DNA-based glycoclusters and binding to Pseudomonas aeruginosa lectin (PA-IIL) » Bioconjugate Chem. 2007, 18, 1637–1643.
  83. Chevolot, Y.; Bouillon, C.; Vidal, S.; Morvan, F.; Meyer, A.; Cloarec, J.-P.; Jochum, A.; Praly, J.-P.; Vasseur J.-J.; Souteyrand, E. « DNA-based carbohydrate biochips: A platform for surface glyco-engineering » Angew. Chem. Int. Ed. 2007, 46, 2398–2402.
  84. Aouadi, K.; Vidal, S.; Msaddek, M.; Praly, J.-P. « Cycloadditions of chiral nitrones to racemic 3-substituted butenes: A direct access with kinetic resolution to enantiopure dihydroxylated amino acids » Synlett 2006, 3299–3303.
  85. Meyer, A.; Bouillon, C.; Vidal, S.; Vasseur, J.-J.; Morvan, F. « A versatile reagent for the synthesis of 5’-phosphorylated, 5’-thiophosphorylated or 5’-phosphoramidate-conjugated oligonucleotides » Tetrahedron Lett. 2006, 47, 8867–8871.
  86. Vidal, S.; Bruyère, I.; Malleron, A.; Augé, C.; Praly, J.-P. « Photo-induced radical addition of glycosyl bromides to diethyl vinylphosphonate: C-glycosyl analogues of natural nucleotide diphosphate sugars as glycosyltransferase inhibitors » Bioorg. Med. Chem. 2006, 14, 7293–7301.
  87. Benltifa, M.; Vidal, S.; Fenet, B.; Msaddek, M.; Goekjian, P.G.; Praly, J.-P.; Brunyánszki, A.; Docsa, T.; Gergely, P. « In Search of Glycogen Phosphorylase Inhibitors: 5-Substituted 3-C-glucopyranosyl-1,2,4-oxadiazoles from b-D-glucopyranosyl cyanides upon cyclization of O-acyl-amidoxime intermediates » Eur. J. Org. Chem. 2006, 4242–4256.
  88. Benltifa, M.; Vidal, S.; Gueyrard, D.; Goekjian, P.G.; Msaddek, M.; Praly, J.-P. « 1,3-Dipolar cycloaddition reactions on carbohydrate-based templates: synthesis of spiro-isoxazolines and 1,2,4-oxadiazoles as glycogen phosphorylase inhibitors » Tetrahedron Lett. 2006, 47, 6143–6147.
  89. Bouillon, C.; Meyer, A.; Vidal, S.; Jochum, A.; Chevolot, Y.; Cloarec, J.-P.; Praly, J.-P.; Vasseur, J.-J.; Morvan, F. « Microwave assisted “click” chemistry for the synthesis of multiple labeled-carbohydrate oligonucleotides on solid support » J. Org. Chem. 2006, 71, 4700–4702.
  90. Compain, P.; Desvergnes, V.; Ollivier, C.; Robert, F.; Suzenet, F.; Barboiu, M.; Belmont, P.; Blériot, Y.; Bolze, F.; Bouquillon, S.; Bourguet, E.; Braida, B.; Constantieux, T.; Désaubry, L.; Dupont, D.; Gastaldi, S.; Jérome, F.; Legoupy, S.; Marat, X.; Migaud, M.; Moitessier, N.; Papot, S.; Peri, F.; Petit, M.; Py, S.; Schulz, E.; Tranoy-Opalinski, I.; Vauzeilles, B.; Vayron, P.; Vergnes, L.; Vidal, S.; Wilmouth, S. « Looking forward: A glance into the future of organic chemistry » New J. Chem. 2006, 30, 823–831.
  91. Compain, P.; Desvergnes, V.; Ollivier, C.; Robert, F.; Suzenet, F.; Barboiu, M.; Belmont, P.; Blériot, Y.; Bolze, F.; Bouquillon, S.; Bourguet, E.; Braida, B.; Constantieux, T.; Désaubry, L.; Dupont, D.; Gastaldi, S.; Jérome, F.; Legoupy, S.; Marat, X.; Migaud, M.; Moitessier, N.; Papot, S.; Peri, F.; Petit, M.; Py, S.; Schulz, E.; Tranoy-Opalinski, I.; Vauzeilles, B.; Vayron, P.; Vergnes, L.; Vidal, S.; Wilmouth, S. « Alchimies futures: Compte rendu de l’expérience ESYOP » C. R. Chimie 2006, 9, 127–140.
  92. Nelson, A.; Belitsky, J.M.; Vidal, S.; Joiner, S.C.; Baum, L.G.; Stoddart, J.F. « A self-assembled multivalent polypseudorotaxane for binding Galectin-1 » J. Am. Chem. Soc. 2004, 126, 11914–11922.
  93. Mouffouk, M.; Vidal, S.; Montero, J.-L., Morère, A. « Selective removal of benzyl carbonate used as a protecting group in carbohydrate chemistry » Synth. Commun. 2004, 34, 303–307.
  94. Kalovidouris, S.A.; Blixt, O.; Nelson, A.; Vidal, S.; Turnbull, W.B.; Paulson, J.C.; Stoddart, J.F. « Chemically defined sialoside scaffolds for investigation of multivalent interactions with sialic acid binding proteins » J. Org. Chem. 2003, 68, 8485–8493.
  95. Nelson, A.; Star, A.; Vidal, S.; Stoddart, J.F. « Amplification of dynamic chiral crown ether complexes during cyclic acetal formation » Angew. Chem. Int. Ed. 2003, 42, 4220–4224.
  96. Vidal, S.; Montero, J.-L.; Morère, A. « A flexible synthetic route to mannose 6-phosphonate–cholesteryl conjugate »:Heteroat. Chem. 2003, 14, 241–246.
  97. Vidal, S.; Garcia, M.; Montero, J.-L.; Morère A. « Synthesis and biological evaluation of new mannose 6-phosphate analogues » Bioorg. Med. Chem. 2002, 10, 4051–4056.
  98. Vidal, S.; Montero, J.-L.; Leydet, A.; Morère, A. « A flexible route to mannose 6-phosphonate functionalized derivatives » Phosphorus, Sulfur & Silicon 2002, 177, 2395–2409.
  99. Vidal, S. « Bismuth(III) derivatives: New catalysts » Synlett 2001, 7, 1194–1195.
  100. Vidal, S.; Vidil, C.; Morère, A.; Garcia, M.; Montero, J.-L. « Synthesis and biological evaluation of two mannose 6-phosphate analogs » Eur. J. Org. Chem. 2000, 3433–3437.
  101. Vidil, C.; Vidal, S.; Morère, A.; Montero, J.-L. « Synthèse de mannose 6-phosphonates, analogues isostères du mannose 6-phosphate » Phosphorus, Sulfur & Silicon 2000, 158, 125–139.
Modern Synthetic Methods in Carbohydrate Chemistry, From Monosaccharides to Complex Glycoconjugates

http://eu.wiley.com/WileyCDA/WileyTitle/productCd-3527332847.html

Maison d’édition: Wiley-VCH Verlag GmbH

ISBN: 978-3-527-33284-7

Co-éditeur: Dr Daniel B. Werz

Année de parution: 2013

Ce livre de 12 chapitres a pour but de regrouper les techniques récentes et modernes de glycochimie qui sont directement liées à des problèmes de chimie organique et qui devraient donc intéresser autant les glycochimistes que les chimistes organiciens.

 
 
Carbohydrate Chemistry: Proven Synthetic Methods – Volume 3

http://www.crcpress.com/browse/series/crccarchepro

Maison d’édition: CRC Press – Taylor&Francis Group

ISBN: 9781138894242

Co-éditeur: Prof. René Roy (Université du Québec à Montréal (UQAM, Canada)

Année de parution: 2014

Ce livre a pour but de regrouper les méthodes de synthèse fiables et vérifiées en glycochimie un peu comme la série de livres « Organic Reactions » en chimie organique ou encore « Methods in Carbohydrate Chemistry » en glycochimie qui a malheureusement été abandonnée depuis plusieurs années.

 
 
Protecting Groups, Strategies and Applications in Carbohydrate Chemistry

http://eu.wiley.com/WileyCDA/WileyTitle/productCd-3527340106.html

Maison d’édition: Wiley-VCH

ISBN: 978-3-527-34010-1

Année de parution: 2019

Ce livre de 17 chapitres regroupe les groupements protecteurs utilisés en chimie des sucres.

2015-2018 Prime d’Encadrement Doctoral et de Recherche (PEDR) du CNRS

2014 Prix Jeune Chercheur du Groupe Français des Glycosciences (GFG)

2011-2014 Prime d’Excellence Scientifique (PES) du CNRS

2007 Prix André Fournet – Bernard Verbert du Groupe Français des Glucides

2019-             Associate Editor de Frontiers in Chemistry

2017-             Membre de la Société Chimique de France

2017-             Membre de l’Editorial Board de Frontiers in Chemistry

2015-             Membre de l’Editorial Board de Carbohydrate Research (Elsevier)

2015-2017     Associate Editor de RSC Advances (Royal Society of Chemistry, UK)

2014-2015     Membre de l’Advisory Board de RSC Advances (Royal Society of Chemistry, UK)

2006-2014     Président du Groupe Lyonnais des Glyco-Sciences (http://glgs.univ-lyon1.fr)

Depuis 2004 Membre du Groupe Français des Glycosciences

2018 Organisateur de “Supr@Lyon” (200 participants internationaux, 17 conférenciers invités dont 2 Prix Nobel de Chimie 1987 et 2016, 10 communications orales, budget = 65 k€)

2011 Organisateur du “European Young Investigators Workshop – Carbohydrate Chemistry: From Synthesis to Applications” (9 conférenciers invités, 40 communications orales, budget = 36 k€)

CNRS Research Associate DR2
(ORCID, @SebVidalChem)

ICSN-CNRS Bât. 27

1, avenue de la Terrasse

91190 Gif-sur-Yvette France

Sebastien.VIDAL@cnrs.fr

+33 1 69 82 45 95