Institut de Chimie des
Substances Naturelles

Select menu item

Recent Publications

HomeResearch DepartmentsNatural Products and Medicinal Chemistry...Functional Chemistry - Chemical Ecology...Recent Publications

2024

  • [DOI] Dung, N.; Levasseur, M.; Segret, J.; Sorres, J.; Hebra, T.; Touboul, D.; Eparvier, V.. Identification of Defensive Antimicrobial Compounds from Environmental Serratia Marcescens SNB-CN88 Strain Associated with Macro-holobiont (termite Nest) Using a Molecular Network Approach. Comptes Rendus. Chimie 2024, 26 (S2), 1–13. doi:10.5802/crchim.259

2023

  • [DOI] Pellissier, L.; Gaudry, A.; Vilette, S.; Lecoultre, N.; Rutz, A.; Allard, P.-M.; Marcourt, L.; Queiroz, E. F.; Chave, J.; Eparvier, V.; Stien, D.; Gindro, K.; Wolfender, J.-L.. Comparative Metabolomic Study of Fungal Foliar Endophytes and Their Long-lived Host Astrocaryum Sciophilum: A Model for Exploring the Chemodiversity of Host-microbe Interactions. Frontiers in Plant Science 2023, 14. doi:10.3389/fpls.2023.1278745
  • [DOI] Levasseur, M.; Nicol, E.; Elie, N.; Houël, E.; Eparvier, V.; Touboul, D.. Spatialized Metabolomic Annotation Combining MALDI Imaging and Molecular Networks. Analytical Chemistry 2023, 96 (1), 18–22. doi:10.1021/acs.analchem.3c03482
  • [DOI] Levasseur, M.; Santerre, C.; Segret, J.; Elie, N.; Genty, C.; Estevez, Y.; Amusant, N.; Houël, E.; Eparvier, V.; Touboul, D.. Composition of Antifungal Volatile Organic Compounds in Sextonia Rubra Fruit by Molecular Networks. Comptes Rendus. Chimie 2023, 26 (S2), 1–13. doi:10.5802/crchim.248
  • [DOI] Hebra, T.; Eparvier, V.; Touboul, D.. Nitrogen Enriched Solid-state Cultivation for the Overproduction of Azaphilone Red Pigments by Penicillium Sclerotiorum SNB-CN111. Journal of Fungi 2023, 9 (2), 156. doi:10.3390/jof9020156

2022

  • [DOI] Hebra, T.; Pollet, N.; Touboul, D.; Eparvier, V.. Combining OSMAC , Metabolomic and Genomic Methods for the Production and Annotation of Halogenated Azaphilones and Ilicicolins in Termite Symbiotic Fungi. Scientific Reports 2022, 12 (1). doi:10.1038/s41598-022-22256-3
  • [DOI] Houël, E.; Ginouves, M.; Azas, N.; Bourreau, E.; Eparvier, V.; Hutter, S.; Knittel-Obrecht, A.; Jahn-Oyac, A.; Prévot, G.; Villa, P.; Vonthron-Sénécheau, C.; Odonne, G.. Treating Leishmaniasis in Amazonia, Part 2: Multi-target Evaluation of Widely Used Plants to Understand Medicinal Practices. Journal of Ethnopharmacology 2022, 289, 115054. doi:10.1016/j.jep.2022.115054
  • [DOI] Levasseur, M.; Hebra, T.; Elie, N.; Guérineau, V.; Touboul, D.; Eparvier, V.. Classification of Environmental Strains from Order to Genus Levels Using Lipid and Protein MALDI - ToF Fingerprintings and Chemotaxonomic Network Analysis. Microorganisms 2022, 10 (4), 831. doi:10.3390/microorganisms10040831
  • [DOI] Sorres, J.; Hebra, T.; Elie, N.; Leman-Loubière, C.; Grayfer, T.; Grellier, P.; Touboul, D.; Stien, D.; Eparvier, V.. Antiparasitic Ovalicin Derivatives from Pseudallescheria Boydii, a Mutualistic Fungus of French Guiana Termites. Molecules 2022, 27 (4), 1182. doi:10.3390/molecules27041182

2021

  • [DOI] Fahed, L.; Beyrouthy, M.; Ouaini, N.; Eparvier, V.; Stien, D.; Vitalini, S.; Iriti, M.. Antimicrobial Activity and Synergy Investigation of Hypericum Scabrum Essential Oil with Antifungal Drugs. 2021, 26 (21), 6545. doi:10.3390/molecules26216545
  • [DOI] Barthélemy, M.; Elie, N.; Genta-Jouve, G.; Stien, D.; Touboul, D.; Eparvier, V.. Identification of Antagonistic Compounds Between the Palm Tree Xylariale Endophytic Fungi and the Phytopathogen Fusarium Oxysporum. Journal of Agricultural and Food Chemistry 2021. doi:10.1021/acs.jafc.1c03141
  • [DOI] Pellissier, L.; Koval, A.; Marcourt, L.; Queiroz, E.; Lecoultre, N.; Leoni, S.; Quiros-Guerrero, L.-M.; Barthélémy, M.; Duivelshof, B.; Guillarme, D.; Tardy, S.; Eparvier, V.; Perron, K.; Chave, J.; Stien, D.; Gindro, K.; Katanaev, V.; Wolfender, J.-L.. Isolation and Identification of Isocoumarin Derivatives with Specific Inhibitory Activity Against Wnt Pathway and Metabolome Characterization of Lasiodiplodia Venezuelensis. Frontiers in Chemistry 2021, 9. doi:10.3389/fchem.2021.664489
  • [DOI] Pellissier, L.; Leoni, S.; Marcourt, L.; Queiroz, E.; Lecoultre, N.; Quiros-Guerrero, L.-M.; Barthélémy, M.; Eparvier, V.; Chave, J.; Stien, D.; Gindro, K.; Perron, K.; Wolfender, J.-L.. Characterization of Pseudomonas Aeruginosa Quorum Sensing Inhibitors from the Endophyte Lasiodiplodia Venezuelensis and Evaluation of Their Antivirulence Effects by Metabolomics. Microorganisms 2021, 9 (9), 1807. doi:10.3390/microorganisms9091807
  • [DOI] Hebra, T.; Elie, N.; Poyer, S.; Elslande, E.; Touboul, D.; Eparvier, V.. Dereplication, Annotation, and Characterization of 74 Potential Antimicrobial Metabolites from Penicillium Sclerotiorum Using T- SNE Molecular Networks. Metabolites 2021, 11 (7), 444. doi:10.3390/metabo11070444

2020

  • [DOI] Barthélemy, M.; Guérineau, V.; Genta-Jouve, G.; Roy, M.; Chave, J.; Guillot, R.; Pellissier, L.; Wolfender, J.-L.; Stien, D.; Eparvier, V.; Touboul, D.. Identification and Dereplication of Endophytic Colletotrichum Strains by MALDI TOF Mass Spectrometry and Molecular Networking. Scientific Reports 2020, 10 (1). doi:10.1038/s41598-020-74852-w
  • [DOI] Hebra, T.; Eparvier, V.; Touboul, D.. Atmospheric Pressure Photoionization Versus Electrospray for the Dereplication of Highly Conjugated Natural Products Using Molecular Networks. Journal of Chromatography A 2020, 1630, 461533. doi:10.1016/j.chroma.2020.461533
  • [DOI] Brel, O.; Touré, S.; Levasseur, M.; Lechat, C.; Pellissier, L.; Wolfender, J.-L.; Van-Elslande, E.; Litaudon, M.; Dusfour, I.; Stien, D.; Eparvier, V.. Paecilosetin Derivatives as Potent Antimicrobial Agents from Isaria Farinosa. Journal of Natural Products 2020, 83 (10), 2915–2922. doi:10.1021/acs.jnatprod.0c00444
  • [DOI] André, A.; Touré, A.; Stien, D.; Eparvier, V.. 2,5-diketopiperazines Mitigate the Amount of Advanced Glycation End Products Accumulated with Age in Human Dermal Fibroblasts. International Journal of Cosmetic Science 2020, 42 (6), 596–604. doi:10.1111/ics.12655
  • [DOI] Sorres, J.; André, A.; Elslande, E.; Stien, D.; Eparvier, V.. Potent and Non-cytotoxic Antibacterial Compounds Against Methicillin-resistant Staphylococcus Aureus Isolated from Psiloxylon Mauritianum, A Medicinal Plant from Reunion Island. Molecules 2020, 25 (16), 3565. doi:10.3390/molecules25163565
  • [DOI] Arias, M.; Quiliano, M.; Bourgeade-Delmas, S.; Fabing, I.; Chantal, I.; Berthier, D.; Minet, C.; Eparvier, V.; Sorres, J.; Stien, D.; Galiano, S.; Aldana, I.; Valentin, A.; Garavito, G.; Deharo, E.. Alsinol, an Arylamino Alcohol Derivative Active Against Plasmodium, Babesia, Trypanosoma, and Leishmania: Past and New Outcomes. Parasitology Research 2020, 119 (10), 3503–3515. doi:10.1007/s00436-020-06832-y
  • [DOI] Peyrat, L.-A.; Eparvier, V.; Eydoux, C.; Guillemot, J.-C.; Litaudon, M.; Stien, D.. Carneic Acids from an Endophytic Phomopsis Sp. As Dengue Virus Polymerase Inhibitors. Journal of Natural Products 2020, 83 (8), 2330–2336. doi:10.1021/acs.jnatprod.9b01169
  • [DOI] Hoang, T.; Barthélemy, M.; Lami, R.; Stien, D.; Eparvier, V.; Touboul, D.. Annotation and Quantification of N-acyl Homoserine Lactones Implied in Bacterial Quorum Sensing by Supercritical-fluid Chromatography Coupled with High-resolution Mass Spectrometry. Analytical and Bioanalytical Chemistry 2020, 412 (10), 2261–2276. doi:10.1007/s00216-019-02265-4
  • [DOI] Falkowski, M.; Jahn-Oyac, A.; Odonne, G.; Flora, C.; Estevez, Y.; Touré, S.; Boulogne, I.; Robinson, J.-C.; Béreau, D.; Petit, P.; Azam, D.; Coke, M.; Issaly, J.; Gaborit, P.; Stien, D.; Eparvier, V.; Dusfour, I.; Houël, E.. Towards the Optimization of Botanical Insecticides Research: Aedes Aegypti Larvicidal Natural Products in French Guiana. Acta Tropica 2020, 201, 105179. doi:10.1016/j.actatropica.2019.105179

2019

  • [DOI] Mai, P.-Y.; Levasseur, M.; Buisson, D.; Touboul, D.; Eparvier, V.. Identification of Antimicrobial Compounds from Sandwithia Guyanensis-associated Endophyte Using Molecular Network Approach. Plants 2019, 9 (1), 47. doi:10.3390/plants9010047
  • [DOI] Donald, J.; Barthélemy, M.; Gazal, N.; Eveno, Y.; Manzi, S.; Eparvier, V.; Stien, D.; Roy, M.. Tropical Palm Endophytes Exhibit Low Competitive Structuring When Assessed Using Co-occurrence and Antipathogen Activity Analysis. 2019, 2. doi:10.3389/ffgc.2019.00086
  • [DOI] Khoury, M.; Beyrouthy, M.; Ouaini, N.; Eparvier, V.; Stien, D.. Hirtellina Lobelii DC. Essential Oil, Its Constituents, Its Combination with Antimicrobial Drugs and Its Mode of Action. Fitoterapia 2019, 133, 130–136. doi:10.1016/j.fitote.2019.01.001
  • [DOI] Rodrigues, A.; Eparvier, V.; Odonne, G.; Amusant, N.; Stien, D.; Houël, E.. The Antifungal Potential of (z)-ligustilide and the Protective Effect of Eugenol Demonstrated by a Chemometric Approach. Scientific Reports 2019, 9 (1), 8729. doi:10.1038/s41598-019-45222-y
  • [DOI] Touré, S.; Desrat, S.; Pellissier, L.; Allard, P.-M.; Wolfender, J.-L.; Dusfour, I.; Stien, D.; Eparvier, V.. Characterization, Diversity, and Structure-activity Relationship Study of Lipoamino Acids from Pantoea Sp. And Synthetic Analogues. International Journal of Molecular Sciences 2019, 20 (5), 1083. doi:10.3390/ijms20051083
  • [DOI] Barthélemy, M.; Elie, N.; Pellissier, L.; Wolfender, J.-L.; Stien, D.; Touboul, D.; Eparvier, V.. Structural Identification of Antibacterial Lipids from Amazonian Palm Tree Endophytes Through the Molecular Network Approach. International Journal of Molecular Sciences 2019, 20 (8), 2006. doi:10.3390/ijms20082006

2018

  • [DOI] André, A.; Wdzieczak-Bakala, J.; Touré, A.; Stien, D.; Eparvier, V.. A Method to Quantify Intracellular Glycation in Dermal Fibroblasts Using Liquid Chromatography Coupled to Fluorescence Detection – Application to the Selection of Deglycation Compounds of Dermatological Interest. Journal of Chromatography B 2018, 1100-1101, 100–105. doi:10.1016/j.jchromb.2018.09.034
  • [DOI] Nasr, S.; Lutz, M.; Amoozegar, M.; Eparvier, V.; Stien, D.; Fazeli, S.; Yurkov, A.. Graphiola Fimbriata: The First Species of Graphiolaceae (exobasidiales, Basidiomycota) Described Only Based on Its Yeast Stage. Mycological Progress 2018, 18 (3), 359–368. doi:10.1007/s11557-018-1450-1
  • [DOI] Remy, S.; Olivon, F.; Desrat, S.; Blanchard, F.; Eparvier, V.; Leyssen, P.; Neyts, J.; Roussi, F.; Touboul, D.; Litaudon, M.. Structurally Diverse Diterpenoids from Sandwithia Guyanensis. Journal of Natural Products 2018. doi:10.1021/acs.jnatprod.7b01025
  • [DOI] Sorres, J.; Sabri, A.; Brel, O.; Stien, D.; Eparvier, V.. Ilicicolinic Acids and Ilicicolinal Derivatives from the Fungus Neonectria Discophora SNB-CN63 Isolated from the Nest of the Termite Nasutitermes Corniger Found in French Guiana Show Antimicrobial Activity. Phytochemistry 2018, 151, 69–77. doi:10.1016/j.phytochem.2018.04.003
  • [DOI] Touré, S.; Barthélémy, M.; Sorres, J.; Genta-Jouve, G.; Dusfour, I.; Eparvier, V.; Stien, D.. Mucorolactone, a Macrolactone from Mucor Sp. SNB-VECD13A, a Fungus Isolated from the Cuticle of a Vespidae Species. Organic Letters 2018, 20 (13), 3780–3783. doi:10.1021/acs.orglett.8b01367
  • [DOI] Khoury, M.; Beyrouthy, M.; Eparvier, V.; Ouaini, N.; Stien, D.. Chemical Diversity and Antimicrobial Activity of the Essential Oils of Four Apiaceae Species Growing Wild in Lebanon. Journal of Essential Oil Research 2018, 30 (1), 25–31. doi:10.1080/10412905.2017.1372314
Our group
ICSN Strain Library

ThemeREX © 2024 All Rights Reserved