Congratulations to Stéphanie Norsikian and co-workers for their publication presenting the total synthesis of Tiacumicin B, a natural macrolide with antibiotic properties for the treatment of intestinal Clostridium difficile infections. Highly beta-diastereoselective glycosylations through the combination of a 3-O-picoloyl group and an anomeric phenylsulfoxide group placed on glycosyl donors.
Work carried out under the supervision of Stéphanie Norsikian at the Chemical Biology department in collaboration with the team of Emmanuel Roulland at Université de Paris and recently published in Angewandte Chemie, Int. Ed. https://doi.org/10.1002/anie.202000231
Welcome to Zarra who’s joining our team as Post-Doc thanks to ANR JCJC “SmartNanoCoat” grant of Dr Stéphanie Deville-Foillard.