CV E. Lescop

  • 2018 – present : Part-time Visiting Scientist in TangLab, WIPM (Wuhan, China)
  • 2013 : Habilitation à Diriger des Recherches (HDR)
  • 2007 – present : CNRS research associate at ICSN – Université Paris-Saclay
  • 2006 – 2007 : Post-doctoral Fellow at Institute of Structural Biology (Grenoble)
  • 2004 – 2006 : Post-doctoral Fellow at Beijing NMR Center (Peking University)
  • 2000 – 2003 : Ph.D. student at ICSN
  • 1996 – 1999 : Elève at the Ecole Polytechnique (Palaiseau)

Nuclear Magnetic Resonance (NMR) spectroscopy provides a wealth of information about the structure and dynamics of biomolecules in solution as well as of their complexes. As such, it highly contributes to our understanding of the molecular mechanisms that underly life. Such knowledge is fundamental not only for the general quest for a better understanding of nature but is also required for rational approaches in health or agronomy industry.

My research interests lie in the development of NMR methods, in particular to speed up NMR data collection and the application of NMR to understand the role of interdomain dynamics in the catalytic cycle of the human CPR, the role of heme orientation in the function of the hexacoordinated human neuroglobin and the structural and dynamics study of microcins. More recently I started a research program about the interactome of TCTP in the context of tumor reversion and studies on the release of peptides encapsulated in liposomes.

Complete list

[1] Malard F, Assrir N, Alami M, Messaoudi S, Lescop E, Ha-Duong T. J Mol Biol. 2018, 430(11), 1621-1639.

[2] Frances, O., Fatemi, F., Pompon, D., Guittet, E., Sizun, C., Perez, J., Lescop, E., and Truan, G. Biophys J. 2015108, 1527-1536.

[3] Bocahut, A., Derrien, V., Bernad, S., Sebban, P., Sacquin-Mora, S., Guittet, E., and Lescop, E. J Biol Inorg Chem. 2013, 18, 111-122.

[4] Vincent, B., Morellet, N., Fatemi, F., Aigrain, L., Truan, G., Guittet, E., and Lescop, E. J Mol Biol. 2012, 420, 296-309.

[5] Brutscher, B., and Lescop, E. Methods Mol Biol. 2012, 831, 407-428.

  • ANR Allosig and Ghredyn (with JL Banères, L. Catoire)
  • Erbb2Cter and Flexiplex (with C. van Heijenoort)
  • Midiazone (with C. Bouton), Frataxur (with B. d’Autréaux)
  • C. Bouton, MP. Golinelli-Cohen (MitoNEET, ICSN)
  • Y. Li, S. Zirah, S. Rebuffat (microcins, MNHN, Paris)
  • L. Catoire (IBPC)
  • A. Telerman (IGR)

since 2009 : Master Engineering and Chemistry of Biomolecules of Paris-Saclay University

since 2009 : Coordinator of the Gif-node for NMR practical wokshop Gigrill

since 2013 : Coorganizer of the Renafobis workshop Ecole d’Oléron

2010 : UNESCO Chair Ramallah (Palestine)

  • Invited Professor by PROTEO network at INRS, 2017
  • Elected member of the CNRS Comité National (section 16, 2012-2016)
  • Active member of the Renafobis network for Integrative Structural Biology
  • Representative of IR-RMN for industrial affairs

CNRS Research Associate CRCN
(ORCID, ResearchGate)

ICSN-CNRS Bât. 23B

1, avenue de la Terrasse

91190 Gif-sur-Yvette France

ewen.lescop_at_cnrs.fr

+33 1 69 82 37 64

Education and work experience
  • 2018 – present : Part-time Visiting Scientist in TangLab, WIPM (Wuhan, China)
  • 2013 : Habilitation à Diriger des Recherches (HDR)
  • 2007 – present : CNRS research associate at ICSN – Université Paris-Saclay
  • 2006 – 2007 : Post-doctoral Fellow at Institute of Structural Biology (Grenoble)
  • 2004 – 2006 : Post-doctoral Fellow at Beijing NMR Center (Peking University)
  • 2000 – 2003 : Ph.D. student at ICSN
  • 1996 – 1999 : Elève at the Ecole Polytechnique (Palaiseau)
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